The selected candidate will join the Grup de Recerca Neuromuscular de Badalona (GRENBA), an interdisciplinary team at the IGTP. GRENBA combines clinical, experimental, and computational approaches to advance research on rare neuromuscular diseases, with a particular focus on myotonic dystrophy type 1 (DM1).The fellow will contribute to our research program analyzing biological samples from DM1 patients enrolled in the DM1-Hub, Spain’s national patient registry. At GRENBA, we apply long-read sequencing technologies to investigate the repetitive region associated with DM1, and we use bioinformatics and biostatistics to refine patient stratification and deepen understanding of disease pathophysiology.In addition, the candidate will design and implement innovative transcriptomic and metabolomic methodologies and multi-omics integration approaches to uncover novel mechanisms underlying DM1 and related neuromuscular disorders
OPEN CALL FOR PREDOCTORAL FELLOWSHIP- FPU/ FI-AGAUR Joan Oró
BADALONA
Full-time
Temporary
JOB DESCRIPTION
MAIN RESPONSIBILITIES
The research project will focus on the comprehensive characterization of the molecular pathophysiology of the patients within the DM1-Hub registry. The specific tasks and responsibilities include:
- Study of patient samples through long-read sequencing, focusing on the characterization of the DMPK region (expansion, variants, epigenetics and mosaicism).Integration of multi-omics data, including transcriptomic and metabolomic datasets, to investigate disease mechanisms and identify potential biomarkers.
- Development of proteomic protocols through ELISA and Western Blot for biomarker validation.
- Develop cell lines from patient samples for biomarker validation and preclinical drug testing.
- Maintain accurate experimental records and document results in a reproducible format.
- Collaboration with clinical and experimental teams to ensure translational relevance of the findings and contributions.
- Preparation of scientific publications, conference presentations, and reports derived from the project outcome
QUALIFICATIONS AND EXPERIENCIE
Essential:
- MSc (or equivalent) in Genetics, Biotechnology, Biomedicine, Biochemistry, Biology, Health Sciences, or closely related field.
- Have a minimum average grade of the academic record for undergraduate studies or of the equivalent degree equal to or greater than 8.5 (scale from 0 to 10).
- Competencies and skills: Communication, Teamwork and collaboration, Commitment, Proactivity, Integrity, Critical and Analytical thinking.
- High level of Spanish and English, written and spoken. Catalan is a plus.
- Hands-on experience with wet laboratory techniques, long-read sequencing, NGS, PCR, genomics, proteomics and/or transcriptomics.
- Hands-on experience in cell and tissue culture, aseptic techniques and sterile laboratory practices
- Scientific writing and presentation skills, as evidenced by peer-reviewed publications and conference contributions.
- International experience
WHAT WE OFFER
- The candidate can be only incorporated with an obtention of a FPU-2026, FI-AGAUR-2026 or similar.
- Pre-doctoral contract
- Full-time contract (1628h/year)
- Flexible payment (childminding vouchers + restaurant ticket).
- 23 days holiday and 5 days for personal matters + 2 days for Easter + 2 days for Christmas (pro-rated based on contract)
- Training capsules by the company.
- Be part of an excellent multidisciplinary research centre with the HRS4R badge.
- Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.
HOW TO APPLY
Candidate must comply with the FPU 2026 and FI-AGAUR Predoctoral Fellowships 2026 eligibility criteria set by the calls:
- At the time of joining the host institution and commencing the contract that is the subject of the grant, candidates must hold a bachelor's or university degree with at least 300 ECTS credits (European Credit Transfer and Accumulation System), and a university master's degree, or an equivalent qualification. If the studies leading to the doctorate are a bachelor’s degree, they must be completed at the time of application submission and with the required minimum grade.
- At the time of applying, candidates may not have received in previous calls any aid for the recruitment of predoctoral research personnel in training (FI or FPU) or any grant for the recruitment of predoctoral research staff in training in the departments of universities of the university system of Catalonia (FI SDUR). Nor can they have enjoyed more than 6 months of any other specific contract for predoctoral research personnel in training.
- Nationality: Any.
- Interested persons must attach to the application:
- Motivation letter explaining their interest in the position.
- Updated CV.
- Contact of 2-3 references.
- Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:
- Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.
- Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.
- Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.
Über uns
L'Institut de Recerca Germans Trias i Pujol (IGTP) és un centre de recerca públic situat a Badalona (Barcelonès) que té com a objectiu principal incrementar el coneixement científic per transformar-lo en solucions per millorar la salut i atenció mèdica dels pacients i de la comunitat.
L'Institut està associat a un dels grans hospitals universitaris de l'àrea de Barcelona, l'Hospital Germans Trias i Pujol, i forma part del campus biomèdic de Can Ruti. És un centre CERCA i també està acreditat com a centre d'excel·lència per l'Institut de Salut Carlos III (ISCIII), sent l'encarregat de coordinar la gestió de la recerca i l'estratègia científica del campus, treballant en estreta col·laboració amb els altres centres que s'hi ubiquen.
L'Institut de Recerca Germans Trias i Pujol duu a terme recerca en 9 àrees:
- Càncer
- Ciències de la conducta i abús de substàncies
- Immunologia i inflamació
- Malalties cardiovasculars i respiratòries
- Malalties del fetge i de l'aparell digestiu
- Malalties endocrines i del metabolisme, dels ossos i dels ronyons
- Malalties infeccioses
- Neurociències
- Salut comunitària
Els científics que treballen en aquestes àrees publiquen una mitjana de més de 900 articles per any, contribueixen amb millors protocols de salut i amb nous tractaments, produeixen patents i creen empreses spin-off per millorar la vida dels pacients.